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Munc13 C(2)B-Domain – an Activity-Dependent Ca(2+)-Regulator of Synaptic Exocytosis

Munc13 is a multidomain protein of presynaptic active zones that mediates the priming and plasticity of synaptic vesicle exocytosis, but the mechanisms involved remain unclear. Here, we use biophysical, biochemical, and electrophysiological approaches to demonstrate that the central C(2)B-domain of...

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Bibliografiset tiedot
Päätekijät: Shin, Ok-Ho, Lu, Jun, Rhee, Jeong-Seop, Tomchick, Diana R., Pang, Zhiping P., Wojcik, Sonja, Camacho-Perez, Marcial, Brose, Nils, Machius, Mischa, Rizo, Josep, Rosenmund, Christian, Südhof, Thomas C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916016/
https://ncbi.nlm.nih.gov/pubmed/20154707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1758
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