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Structural Basis for a Munc13–1 Homodimer to Munc13–1/RIM Heterodimer Switch
C (2) domains are well characterized as Ca (2+)/phospholipid-binding modules, but little is known about how they mediate protein–protein interactions. In neurons, a Munc13–1 C (2)A-domain/RIM zinc-finger domain (ZF) heterodimer couples synaptic vesicle priming to presynaptic plasticity. We now show...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1472246/ https://ncbi.nlm.nih.gov/pubmed/16732694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0040192 |
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