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A conformational switch in syntaxin during exocytosis: role of munc18.
Syntaxin 1, an essential protein in synaptic membrane fusion, contains a helical autonomously folded N-terminal domain, a C-terminal SNARE motif and a transmembrane region. The SNARE motif binds to synaptobrevin and SNAP-25 to assemble the core complex, whereas almost the entire cytoplasmic sequence...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1999
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171512/ https://ncbi.nlm.nih.gov/pubmed/10449403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.16.4372 |
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