Mutations at positions 186 and 194 in the HA gene of the 2009 H1N1 pandemic influenza virus improve replication in cell culture and eggs

Obtaining suitable seed viruses for influenza vaccines poses a challenge for public health authorities and manufacturers. We used reverse genetics to generate vaccine seed-compatible viruses from the 2009 pandemic swine-origin influenza virus. Comparison of viruses recovered with variations in resid...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Suphaphiphat, Pirada, Franti, Michael, Hekele, Armin, Lilja, Anders, Spencer, Terika, Settembre, Ethan, Palmer, Gene, Crotta, Stefania, Tuccino, Annunziata B, Keiner, Bjoern, Trusheim, Heidi, Balabanis, Kara, Sackal, Melissa, Rothfeder, Mithra, Mandl, Christian W, Dormitzer, Philip R, Mason, Peter W
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2010
Предметы:
Short Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914672/
https://ncbi.nlm.nih.gov/pubmed/20630098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-7-157
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы