Φορτώνει......
Mutations in the V3 Stem versus the V3 Crown and C4 Region Have Different Effects on the Binding and Fusion Steps of Human Immunodeficiency Virus Type 1 Gp120 Interaction with the CCR5 Coreceptor
The current model for HIV-1 envelope-coreceptor interaction depicts the V3 stem and bridging sheet binding to the CCR5 N-terminus while the V3 crown interacts with the second extracellular loop, which is the coreceptor domain that appears to be relatively more important for fusion and infection. Our...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2006
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2014721/ https://ncbi.nlm.nih.gov/pubmed/17101166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.10.019 |
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