Effect of Amino Acid Substitution of the V3 and Bridging Sheet Residues in Human Immunodeficiency Virus Type 1 Subtype C gp120 on CCR5 Utilization

The V3 loop and the bridging sheet domain of human immunodeficiency virus type 1 (HIV-1) subtype B envelope glycoprotein gp120 have been implicated in CCR5 coreceptor utilization. In this study, mutant envelope glycoproteins of a subtype C isolate containing substitutions in the V3 or C4 region were...

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Bibliographic Details
Main Authors: Suphaphiphat, Pirada, Thitithanyanont, Arunee, Paca-Uccaralertkun, Saowakon, Essex, Max, Lee, Tun-Hou
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC149532/
https://ncbi.nlm.nih.gov/pubmed/12610158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.6.3832-3837.2003
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