Differential Inhibition of Human Immunodeficiency Virus Type 1 Fusion, gp120 Binding, and CC-Chemokine Activity by Monoclonal Antibodies to CCR5

The CC-chemokine receptor CCR5 mediates fusion and entry of the most commonly transmitted human immunodeficiency virus type 1 (HIV-1) strains. We have isolated six new anti-CCR5 murine monoclonal antibodies (MAbs), designated PA8, PA9, PA10, PA11, PA12, and PA14. A panel of CCR5 alanine point mutant...

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Detalhes bibliográficos
Main Authors: Olson, William C., Rabut, Gwénaël E. E., Nagashima, Kirsten A., Tran, Diep N. H., Anselma, Deborah J., Monard, Simon P., Segal, Jeremy P., Thompson, Daniah A. D., Kajumo, Francis, Guo, Yong, Moore, John P., Maddon, Paul J., Dragic, Tatjana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC104194/
https://ncbi.nlm.nih.gov/pubmed/10196311
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