Human RNA Polymerase I-Driven Reverse Genetics for Influenza A Virus in Canine Cells

We have established a human RNA polymerase I (pol I)-driven influenza virus reverse genetics (RG) system in the Madin-Darby canine kidney 33016-PF cell line, which is approved for influenza vaccine manufacture. RNA pol I polymerases are generally active only in cells of species closely related to th...

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Hlavní autoři: Suphaphiphat, Pirada, Keiner, Bjoern, Trusheim, Heidi, Crotta, Stefania, Tuccino, Annunziata Barbara, Zhang, Pu, Dormitzer, Philip R., Mason, Peter W., Franti, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838141/
https://ncbi.nlm.nih.gov/pubmed/20071567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01925-09
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