Zinc transporter (ZnT)8(186-194) is an immunodominant CD8(+) T-cell epitopein HLA-A2(+) type 1 diabetic patients

AIMS/HYPOTHESIS: Anti-zinc transporter (ZnT)8 autoantibodies are commonly detected in type 1 diabetic patients. We hypothesized that ZnT8 is also recognized by CD8+ T cells and aimed at identifying HLA-A2 (A*02:01)-restricted epitope targets. METHODS: Candidate epitopes were selected by ZnT8 plasmid...

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Detalhes bibliográficos
Main Authors: Scotto, M., Afonso, G., Larger, E., Raverdy, C., Lemonnier, F.A., Carel, J.C., Dubois-Laforgue, D., Baz, B., Levy, D., Gautier, J.F., Launey, O., Bruno, G., Boitard, C., Sechi, L.A., Hutton, J.C., Davidson, H.W., Mallone, R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740540/
https://ncbi.nlm.nih.gov/pubmed/22526607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-012-2543-z
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