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ZINC TRANSPORTER 8 (ZNT8) AND BETA CELL FUNCTION
Human pancreatic β cells have exceptionally high zinc content. In β cells the highest zinc concentration is in insulin secretory granules, from which it is co-secreted with the hormone. Uptake of zinc into secretory granules is mainly mediated by zinc transporter 8 (ZnT8), the product of the SLC30A8...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4112161/ https://ncbi.nlm.nih.gov/pubmed/24751356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2014.03.008 |
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