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Human type 1 diabetes is associated with T cell autoimmunity to zinc transporter 8 (ZnT8)

Recently we demonstrated that zinc transporter 8 (ZnT8) is a major target of autoantibodies in human type 1 diabetes (T1D). Since the molecules recognized by T1D autoantibodies are typically also targets of autoreactive T cells, we reasoned that this would likely be the case for ZnT8. To test this h...

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Autors principals: Dang, MyLinh, Rockell, Jennifer, Wagner, Rebecca, Wenzlau, Janet M., Yu, Liping, Hutton, John C., Gottlieb, Peter A., Davidson, Howard W.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088514/
https://ncbi.nlm.nih.gov/pubmed/21471440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003815
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