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MAPPING OF CONFORMATIONAL AUTOANTIBODY EPITOPES IN ZNT8

BACKGROUND: Identification of the major humoral epitopes in ZnT8 will expand the range of biomarkers for human type 1 diabetes (T1D), and may provide clues to the mechanisms governing disease progression. Our initial studies suggested that most ZnT8-reactive sera recognize conformational epitopes in...

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Autores principales: Wenzlau, Janet M., Frisch, Lisa M., Hutton, John C., Davidson, Howard W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664522/
https://ncbi.nlm.nih.gov/pubmed/22069278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dmrr.1266
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