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ZINC TRANSPORTER 8 (ZNT8) AND BETA CELL FUNCTION

Human pancreatic β cells have exceptionally high zinc content. In β cells the highest zinc concentration is in insulin secretory granules, from which it is co-secreted with the hormone. Uptake of zinc into secretory granules is mainly mediated by zinc transporter 8 (ZnT8), the product of the SLC30A8...

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Detalhes bibliográficos
Main Authors: Davidson, Howard W., Wenzlau, Janet M., O’Brien, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112161/
https://ncbi.nlm.nih.gov/pubmed/24751356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2014.03.008
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