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The interrelationship between mitochondrial dysfunction and transcriptional dysregulation in Huntington disease
Huntington disease (HD) is an inherited neuro-degenerative disease caused by an abnormal expansion of the CAG repeat region in the huntingtin (Htt) gene. Although the pathogenic mechanisms by which mutant Htt (mHtt) causes HD have not been fully elucidated, it is becoming increasingly apparent that...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913874/ https://ncbi.nlm.nih.gov/pubmed/20556492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10863-010-9286-7 |
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