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The interrelationship between mitochondrial dysfunction and transcriptional dysregulation in Huntington disease
Huntington disease (HD) is an inherited neuro-degenerative disease caused by an abnormal expansion of the CAG repeat region in the huntingtin (Htt) gene. Although the pathogenic mechanisms by which mutant Htt (mHtt) causes HD have not been fully elucidated, it is becoming increasingly apparent that...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2010
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2913874/ https://ncbi.nlm.nih.gov/pubmed/20556492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10863-010-9286-7 |
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