Rosiglitazone Treatment Prevents Mitochondrial Dysfunction in Mutant Huntingtin-expressing Cells: POSSIBLE ROLE OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-γ (PPARγ) IN THE PATHOGENESIS OF HUNTINGTON DISEASE

Peroxisome proliferator-activated receptor-γ (PPARγ) is a member of the PPAR family of transcription factors. Synthetic PPARγ agonists are used as oral anti-hyperglycemic drugs for the treatment of non-insulin-dependent diabetes. However, emerging evidence indicates that PPARγ activators can also pr...

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Détails bibliographiques
Auteurs principaux: Quintanilla, Rodrigo A., Jin, Youngnam N., Fuenzalida, Karen, Bronfman, Miguel, Johnson, Gail V. W.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2008
Sujets:
Mechanisms of Signal Transduction
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533094/
https://ncbi.nlm.nih.gov/pubmed/18640979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804291200
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