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Role of Mitochondrial Dysfunction in the Pathogenesis of Huntington’s Disease
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder that is caused by a pathological expansion of CAG repeats within the gene encoding for a 350 kD protein called huntingtin. This polyglutamine expansion within huntingtin is the causative factor in the pathogenesis of HD, h...
Bewaard in:
Hoofdauteurs: | , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2009
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757461/ https://ncbi.nlm.nih.gov/pubmed/19622387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2009.07.010 |
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