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Role of Mitochondrial Dysfunction in the Pathogenesis of Huntington’s Disease
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder that is caused by a pathological expansion of CAG repeats within the gene encoding for a 350 kD protein called huntingtin. This polyglutamine expansion within huntingtin is the causative factor in the pathogenesis of HD, h...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2757461/ https://ncbi.nlm.nih.gov/pubmed/19622387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2009.07.010 |
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