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Mitochondrial permeability transition pore induces mitochondria injury in Huntington disease
BACKGROUND: Mitochondrial impairment has been implicated in the pathogenesis of Huntington’s disease (HD). However, how mutant huntingtin impairs mitochondrial function and thus contributes to HD has not been fully elucidated. In this study, we used striatal cells expressing wild type (STHdh(Q7/Q7))...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3878840/ https://ncbi.nlm.nih.gov/pubmed/24330821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-8-45 |
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