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Mitochondrial permeability transition pore induces mitochondria injury in Huntington disease

BACKGROUND: Mitochondrial impairment has been implicated in the pathogenesis of Huntington’s disease (HD). However, how mutant huntingtin impairs mitochondrial function and thus contributes to HD has not been fully elucidated. In this study, we used striatal cells expressing wild type (STHdh(Q7/Q7))...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Quintanilla, Rodrigo A, Jin, Youngnam N, von Bernhardi, Rommy, Johnson, Gail VW
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878840/
https://ncbi.nlm.nih.gov/pubmed/24330821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-8-45
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