Cloning, Heterologous Expression, and Distinct Substrate Specificity of Protein Farnesyltransferase from Trypanosoma brucei

Protein prenylation occurs in the protozoan that causes African sleeping sickness (Trypanosoma brucei), and the protein farnesyltransferase appears to be a good target for developing drugs. We have cloned the α- and β-subunits of T. brucei protein farnesyltransferase (TB-PFT) using nucleic acid prob...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Buckner, Frederick S., Yokoyama, Kohei, Nguyen, Lisa, Grewal, Anita, Erdjument-Bromage, Hediye, Tempst, Paul, Strickland, Corey L., Xiao, Li, Van Voorhis, Wesley C., Gelb, Michael H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913713/
https://ncbi.nlm.nih.gov/pubmed/10749864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M000975200
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky