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Trypanosoma brucei prenylated-protein carboxyl methyltransferase prefers farnesylated substrates.
Carboxyl methylation of the C-terminal prenylated cysteine, which occurs in most farnesylated and geranylgeranylated proteins, is a reversible step and is implicated in the regulation of membrane binding and cellular functions of prenylated proteins such as GTPases. The gene coding for prenylated-pr...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1222931/ https://ncbi.nlm.nih.gov/pubmed/12141948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020277 |
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