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Trypanosoma brucei prenylated-protein carboxyl methyltransferase prefers farnesylated substrates.

Carboxyl methylation of the C-terminal prenylated cysteine, which occurs in most farnesylated and geranylgeranylated proteins, is a reversible step and is implicated in the regulation of membrane binding and cellular functions of prenylated proteins such as GTPases. The gene coding for prenylated-pr...

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Detalhes bibliográficos
Main Authors: Buckner, Frederick S, Kateete, David P, Lubega, George W, Van Voorhis, Wesley C, Yokoyama, Kohei
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222931/
https://ncbi.nlm.nih.gov/pubmed/12141948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020277
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