Caricamento...

Cloning, Heterologous Expression, and Distinct Substrate Specificity of Protein Farnesyltransferase from Trypanosoma brucei

Protein prenylation occurs in the protozoan that causes African sleeping sickness (Trypanosoma brucei), and the protein farnesyltransferase appears to be a good target for developing drugs. We have cloned the α- and β-subunits of T. brucei protein farnesyltransferase (TB-PFT) using nucleic acid prob...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Buckner, Frederick S., Yokoyama, Kohei, Nguyen, Lisa, Grewal, Anita, Erdjument-Bromage, Hediye, Tempst, Paul, Strickland, Corey L., Xiao, Li, Van Voorhis, Wesley C., Gelb, Michael H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2000
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913713/
https://ncbi.nlm.nih.gov/pubmed/10749864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M000975200
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !