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A class of sterol 14-demethylase inhibitors as anti-Trypanosoma cruzi agents
Chronic infection with the protozoan parasite Trypanosoma cruzi is a major cause of morbidity and mortality in Latin America. Drug treatments for the associated illness, Chagas disease, are toxic and frequently unsuccessful. In a screening effort against the drug target protein farnesyltransferase,...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC299928/ https://ncbi.nlm.nih.gov/pubmed/14657358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2535442100 |
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