Potent Anti-Trypanosoma cruzi Activities of Oxidosqualene Cyclase Inhibitors

Trypanosoma cruzi is the protozoan agent that causes Chagas' disease, a major health problem in Latin America. Better drugs are needed to treat infected individuals. The sterol biosynthesis pathway is a potentially excellent target for drug therapy against T. cruzi. In this study, we investigat...

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Bibliografiske detaljer
Main Authors: Buckner, Frederick S., Griffin, John H., Wilson, Aaron J., Van Voorhis, Wesley C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Susceptibility
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90445/
https://ncbi.nlm.nih.gov/pubmed/11257036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.4.1210-1215.2001
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