Cellular Source of Apolipoprotein E4 Determines Neuronal Susceptibility to Excitotoxic Injury in Transgenic Mice

The lipid transport protein apolipoprotein E (apoE) is abundantly expressed in the brain. Its main isoforms in humans are apoE2, apoE3, and apoE4. ApoE4 is the major known genetic risk factor for Alzheimer’s disease and also contributes to the pathogenesis of various other neurological conditions. I...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Buttini, Manuel, Masliah, Eliezer, Yu, Gui-Qiu, Palop, Jorge J., Chang, Shengjun, Bernardo, Aubrey, Lin, Carol, Wyss-Coray, Tony, Huang, Yadong, Mucke, Lennart
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2010
Témata:
Short Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913361/
https://ncbi.nlm.nih.gov/pubmed/20595630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090973
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky