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Chronic Overproduction of Transforming Growth Factor-β1 by Astrocytes Promotes Alzheimer’s Disease-Like Microvascular Degeneration in Transgenic Mice
Cerebrovascular amyloid deposition and microvascular degeneration are frequently associated with Alzheimer’s disease (AD), but the etiology and pathogenetic role of these abnormalities are unknown. Recently, transforming growth factor-β1 (TGF-β1) was implicated in cerebrovascular amyloid formation i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1868631/ https://ncbi.nlm.nih.gov/pubmed/10623661 |
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