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γδTCR ligands and lineage commitment

Two major T lymphocyte lineages - αβ and γδ T cells - develop in the thymus from common precursors. Differentiation of both lineages requires signals coming from TCRs. Development of αβ T cells is driven at early stages by signaling from the pre-TCR, most likely in a ligand-independent fashion, and...

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Autors principals: Kreslavsky, Taras, von Boehmer, Harald
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912151/
https://ncbi.nlm.nih.gov/pubmed/20447836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2010.04.001
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