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TCR-inducible PLZF transcription factor required for innate phenotype of a subset of γδ T cells with restricted TCR diversity

Some γδ and αβ T lymphocytes exhibit an “innate” phenotype associated with rapid cytokine responses. The PLZF transcription factor is essential for the innate phenotype of NKT cells. This report shows that PLZF is likewise responsible for the innate, NKT-like phenotype of Vγ1+Vδ6.3/Vδ6.4+ cells. TCR...

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Detaylı Bibliyografya
Asıl Yazarlar: Kreslavsky, Taras, Savage, Adam K., Hobbs, Robin, Gounari, Fotini, Bronson, Roderick, Pereira, Pablo, Pandolfi, Pier Paolo, Bendelac, Albert, von Boehmer, Harald
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718370/
https://ncbi.nlm.nih.gov/pubmed/19617548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903895106
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