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TCR-inducible PLZF transcription factor required for innate phenotype of a subset of γδ T cells with restricted TCR diversity

Some γδ and αβ T lymphocytes exhibit an “innate” phenotype associated with rapid cytokine responses. The PLZF transcription factor is essential for the innate phenotype of NKT cells. This report shows that PLZF is likewise responsible for the innate, NKT-like phenotype of Vγ1+Vδ6.3/Vδ6.4+ cells. TCR...

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書誌詳細
主要な著者: Kreslavsky, Taras, Savage, Adam K., Hobbs, Robin, Gounari, Fotini, Bronson, Roderick, Pereira, Pablo, Pandolfi, Pier Paolo, Bendelac, Albert, von Boehmer, Harald
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718370/
https://ncbi.nlm.nih.gov/pubmed/19617548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903895106
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