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Pre-TCRα and TCRα Are Not Interchangeable Partners of TCRβ during T Lymphocyte Development

In contrast with the αβ T cell receptor (TCR), the pre-TCR spontaneously segregates to membrane rafts from where it signals in a cell-autonomous fashion. The disparate behaviors of these two receptors may stem either from differences inherent to the distinct developmental stages during which they ar...

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Autori principali: Borowski, Christine, Li, Xiaoyan, Aifantis, Iannis, Gounari, Fotini, von Boehmer, Harald
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213307/
https://ncbi.nlm.nih.gov/pubmed/14993248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031973
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