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Allelic Exclusion in pTα-deficient Mice: No Evidence for Cell Surface Expression of Two T Cell Receptor (TCR)-β Chains, but Less Efficient Inhibition of Endogeneous Vβ→ (D)Jβ Rearrangements in the Presence of a Functional TCR-β Transgene

Although individual T lymphocytes have the potential to generate two distinct T cell receptor (TCR)-β chains, they usually express only one allele, a phenomenon termed allelic exclusion. Expression of a functional TCR-β chain during early T cell development leads to the formation of a pre-T cell rec...

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Bibliografske podrobnosti
Main Authors: Krotkova, Anna, von Boehmer, Harald, Fehling, Hans Jörg
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1997
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199014/
https://ncbi.nlm.nih.gov/pubmed/9271592
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