Allelic Exclusion and Peripheral Reconstitution by TCR Transgenic T Cells Arising From Transduced Human Hematopoietic Stem/Progenitor Cells

Transduction and transplantation of human hematopoietic stem/progenitor cells (HSPC) with the genes for a T-cell receptor (TCR) that recognizes a tumor-associated antigen may lead to sustained long-term production of T cells expressing the TCR and confer specific antitumor activity. We evaluated thi...

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Detalhes bibliográficos
Main Authors: Giannoni, Francesca, Hardee, Cinnamon L, Wherley, Jennifer, Gschweng, Eric, Senadheera, Shantha, Kaufman, Michael L, Chan, Rebecca, Bahner, Ingrid, Gersuk, Vivian, Wang, Xiaoyan, Gjertson, David, Baltimore, David, Witte, Owen N, Economou, James S, Ribas, Antoni, Kohn, Donald B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666644/
https://ncbi.nlm.nih.gov/pubmed/23380815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.8
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