CD4+CD25− T cells transduced to express MHC class I-restricted epitope specific TCR synthesize Th1 cytokines and exhibit MHC class I-restricted cytolytic effector function in a human melanoma model

Cytolytic T cell-centric active specific and adoptive immunotherapeutic approaches might benefit from the simultaneous engagement of CD4+ T cells. Considering the difficulties in simultaneously engaging CD4+ and CD8+ T cells in tumor immunotherapy -- especially in an antigen specific manner -- “redi...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Chhabra, Arvind, Yang, Lili, Wang, Pin, Comin-Anduix, Begoña, Das, Raja, Chakraborty, Nitya G., Ray, Swagatam, Mehrotra, Shikhar, Yang, Haiguang, Hardee, Cinnamon L., Hollis, Roger, Dorsky, David I., Koya, Richard, Kohn, Donald B., Ribas, Antoni, Economou, James S., Baltimore, David, Mukherji, Bijay
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715965/
https://ncbi.nlm.nih.gov/pubmed/18606658
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы