CD4+CD25− T cells transduced to express MHC class I-restricted epitope specific TCR synthesize Th1 cytokines and exhibit MHC class I-restricted cytolytic effector function in a human melanoma model

Cytolytic T cell-centric active specific and adoptive immunotherapeutic approaches might benefit from the simultaneous engagement of CD4+ T cells. Considering the difficulties in simultaneously engaging CD4+ and CD8+ T cells in tumor immunotherapy -- especially in an antigen specific manner -- “redi...

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מידע ביבליוגרפי
Main Authors: Chhabra, Arvind, Yang, Lili, Wang, Pin, Comin-Anduix, Begoña, Das, Raja, Chakraborty, Nitya G., Ray, Swagatam, Mehrotra, Shikhar, Yang, Haiguang, Hardee, Cinnamon L., Hollis, Roger, Dorsky, David I., Koya, Richard, Kohn, Donald B., Ribas, Antoni, Economou, James S., Baltimore, David, Mukherji, Bijay
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715965/
https://ncbi.nlm.nih.gov/pubmed/18606658
תגים: הוספת תג
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