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Death Receptor Independent Activation Induced Cell Death (AICD) in Human Melanoma Antigen Specific MHC class I-Restricted TCR Engineered CD4 T Cells

Engaging CD4 T cells in anti-tumor immunity has been quite challenging, especially in an antigen specific manner, since most human solid tumors usually do not express MHC class II molecules. We have recently shown that human CD4 T cells engineered to express a human melanoma associated antigenic epi...

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Detalhes bibliográficos
Main Authors: Chhabra, Arvind, Mukherji, Bijay
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779684/
https://ncbi.nlm.nih.gov/pubmed/23935194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202350
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