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Positive selection of an MHC class-I restricted TCR in the absence of classical MHC class I molecules
The H-2L(d) alloreactive 2C T cell receptor (TCR) is commonly considered as being positively selected on the H-2K(b) molecule. Surprisingly, 2C TCR(+) CD8(+) single-positive T cells emerge in massive numbers in fetal thymic organ culture originating from 2C transgenic, H-2K(b)D(b−/−) (2C(+)K(b)D(b−/...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC34687/ https://ncbi.nlm.nih.gov/pubmed/11404484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.141143298 |
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