Antimicrobial activity of MHC class I-restricted CD8+ T cells in human tuberculosis

Studies of mouse models of tuberculosis (TB) infection have indicated a central role for MHC class I-restricted CD8+ T cells in protective immunity. To define antigens and epitopes of Mycobacterium tuberculosis (MTB) proteins that are presented by infected cells to CD8+ T cells, we screened 40 MTB p...

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Autori principali: Cho, Sungae, Mehra, Vijay, Thoma-Uszynski, Sybille, Stenger, Steffen, Serbina, Natalya, Mazzaccaro, Richard J., Flynn, JoAnne L., Barnes, Peter F., Southwood, Scott, Celis, Esteban, Bloom, Barry R., Modlin, Robert L., Sette, Alessandro
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2000
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC17320/
https://ncbi.nlm.nih.gov/pubmed/11035787
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