Adoptive Immunotherapy of Disseminated Leukemia With TCR-transduced, CD8(+) T Cells Expressing a Known Endogenous TCR

Adoptive T-cell immunotherapy has shown promise in the treatment of human malignancies, but the challenge of isolating T cells with high avidity for tumor antigens in each patient has limited application of this approach. The transfer into T cells of T-cell receptor (TCR) genes encoding high-affinit...

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Detalhes bibliográficos
Main Authors: Dossett, Michelle L, Teague, Ryan M, Schmitt, Thomas M, Tan, Xiaoxia, Cooper, Laurence JN, Pinzon, Cristina, Greenberg, Philip D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730935/
https://ncbi.nlm.nih.gov/pubmed/19209146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.300
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