Development of adoptive immunotherapy with KK‐LC‐1‐specific TCR‐transduced γδT cells against lung cancer cells

The present study analyzed the antitumor effect of γδT cells transduced with the TCR of cancer‐specific CTLs to establish forceful cancer‐specific adoptive immunotherapy. We cloned the TCRαβ genes from CTLs showing HLA‐B15 restricted recognition of Kita‐Kyushu lung cancer antigen‐1 (KK‐LC‐1), a canc...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Ichiki, Yoshinobu, Shigematsu, Yoshiki, Baba, Tetsuro, Shiota, Hironobu, Fukuyama, Takashi, Nagata, Yoshika, So, Tetsuya, Yasuda, Manabu, Takenoyama, Mitsuhiro, Yasumoto, Kosei
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648040/
https://ncbi.nlm.nih.gov/pubmed/32780528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14612
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