Development of adoptive immunotherapy with KK‐LC‐1‐specific TCR‐transduced γδT cells against lung cancer cells

The present study analyzed the antitumor effect of γδT cells transduced with the TCR of cancer‐specific CTLs to establish forceful cancer‐specific adoptive immunotherapy. We cloned the TCRαβ genes from CTLs showing HLA‐B15 restricted recognition of Kita‐Kyushu lung cancer antigen‐1 (KK‐LC‐1), a canc...

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Vydáno v:Cancer Sci
Hlavní autoři: Ichiki, Yoshinobu, Shigematsu, Yoshiki, Baba, Tetsuro, Shiota, Hironobu, Fukuyama, Takashi, Nagata, Yoshika, So, Tetsuya, Yasuda, Manabu, Takenoyama, Mitsuhiro, Yasumoto, Kosei
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7648040/
https://ncbi.nlm.nih.gov/pubmed/32780528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14612
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