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Regulation of T cell receptor (TCR) β gene expression by CD3 complex signaling in immature thymocytes: Implications for TCRβ allelic exclusion

During αβ thymocyte development, clonotype-independent CD3 complexes are expressed at the cell surface before the pre-T cell receptor (TCR). Signaling through clonotype-independent CD3 complexes is required for expression of rearranged TCRβ genes. On expression of a TCRβ polypeptide chain, the pre-T...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Biro, Judit, Würch, Andreas, Potocnik, Alexandre J., Falk, Ingrid, Mossmann, Horst, Eichmann, Klaus
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22389/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10097132/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.7.3882
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