Immature thymocytes are protected from deletion early in ontogeny.
Self/non-self discrimination occurs within the thymus, where T cells undergo positive selection to produce a repertoire that recognizes foreign antigen in the context of self major histocompatibility complex proteins and negative selection to eliminate from the repertoire those T cells with self-rea...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48869/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1565628/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.8.3372 |
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