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Adhesion of immature thymocytes to thymic stromal cells through fibronectin molecules and its significance for the induction of thymocyte differentiation.

Only 10-15% of unseparated thymocytes adhered to culture plates precoated with fibronectin (FN), but 60-70% of the CD4-8- (double-negative) thymocyte population did. This population bound to FN but not to collagen, laminin, or vitronectin. Its binding to FN was inhibited by anti-FN antibody or a mix...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Utsumi, K, Sawada, M, Narumiya, S, Nagamine, J, Sakata, T, Iwagami, S, Kita, Y, Teraoka, H, Hirano, H, Ogata, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51942/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1829526/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.13.5685
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