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Early T Cell Receptor β Gene Expression Is Regulated by the Pre-T Cell Receptor–CD3 Complex

We have examined the question of whether there is an additional checkpoint in T cell development that regulates T cell receptor (TCR)-β expression in CD25(+)44(−) thymocytes by mechanisms that are independent of the pre-TCR. Our analysis in various mutant mice indicates that all changes in cytoplasm...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Aifantis, Iannis, Feinberg, Jacqueline, Fehling, Hans Jörg, Di Santo, James P., von Boehmer, Harald
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195557/
https://ncbi.nlm.nih.gov/pubmed/10429678
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