Allelic Exclusion of the T Cell Receptor β Locus Requires the Sh2 Domain–Containing Leukocyte Protein (Slp)-76 Adaptor Protein

Signaling via the pre-T cell receptor (TCR) is required for the proliferative expansion and maturation of CD4(−)CD8(−) double-negative (DN) thymocytes into CD4(+)CD8(+) double-positive (DP) cells and for TCR-β allelic exclusion. The adaptor protein SH2 domain–containing leukocyte protein (SLP)-76 ha...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Aifantis, Iannis, Pivniouk, Vadim I., Gärtner, Frank, Feinberg, Jacqueline, Swat, Wojciech, Alt, Frederick W., von Boehmer, Harald, Geha, Raif S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195661/
https://ncbi.nlm.nih.gov/pubmed/10523607
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados