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Differential role of SLP-76 domains in T cell development and function
The adapter SLP-76 is essential for thymocyte development. SLP-76(−/−) mice were reconstituted with SLP-76 deletion mutant transgenes to examine the role of SLP-76 domains in T cell development and function. The N-terminal domain deletion mutant completely failed to restore thymocyte development. Mi...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The National Academy of Sciences
2002
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC117400/ https://ncbi.nlm.nih.gov/pubmed/11792851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022619199 |
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