Early Activation of Sphingosine Kinase in Mast Cells and Recruitment to FcɛRI Are Mediated by Its Interaction with Lyn Kinase

Sphingosine kinase has been recognized as an essential signaling molecule that mediates the intracellular conversion of sphingosine to sphingosine-1-phosphate. In mast cells, induction of sphingosine kinase and generation of sphingosine-1-phosphate have been linked to the initial rise in Ca(2+), rel...

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Bibliographic Details
Main Authors: Urtz, Nicole, Olivera, Ana, Bofill-Cardona, Elisa, Csonga, Robert, Billich, Andreas, Mechtcheriakova, Diana, Bornancin, Frederic, Woisetschläger, Max, Rivera, Juan, Baumruker, Thomas
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC516729/
https://ncbi.nlm.nih.gov/pubmed/15367693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.19.8765-8777.2004
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