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Early Activation of Sphingosine Kinase in Mast Cells and Recruitment to FcɛRI Are Mediated by Its Interaction with Lyn Kinase

Sphingosine kinase has been recognized as an essential signaling molecule that mediates the intracellular conversion of sphingosine to sphingosine-1-phosphate. In mast cells, induction of sphingosine kinase and generation of sphingosine-1-phosphate have been linked to the initial rise in Ca(2+), rel...

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Autori principali: Urtz, Nicole, Olivera, Ana, Bofill-Cardona, Elisa, Csonga, Robert, Billich, Andreas, Mechtcheriakova, Diana, Bornancin, Frederic, Woisetschläger, Max, Rivera, Juan, Baumruker, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC516729/
https://ncbi.nlm.nih.gov/pubmed/15367693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.19.8765-8777.2004
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