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γδTCR ligands and lineage commitment
Two major T lymphocyte lineages - αβ and γδ T cells - develop in the thymus from common precursors. Differentiation of both lineages requires signals coming from TCRs. Development of αβ T cells is driven at early stages by signaling from the pre-TCR, most likely in a ligand-independent fashion, and...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912151/ https://ncbi.nlm.nih.gov/pubmed/20447836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2010.04.001 |
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