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Inhibition of Methylglyoxal-Mediated Protein Modification in Glyoxalase I Overexpressing Mouse Lenses

Objective. Here we tested the role of Glo I in the prevention of advanced glycation end product (AGE) formation in transgenic mouse lenses. Methods. A transgenic animal line that expressed high levels of human Glo I in the lens was developed from the C57B6 mouse strain. The role of Glo I in the inhi...

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Bibliografische gegevens
Hoofdauteurs: Gangadhariah, Mahesha H., Mailankot, Maneesh, Reneker, Lixing, Nagaraj, Ram H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910474/
https://ncbi.nlm.nih.gov/pubmed/20671953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/274317
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