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Glycation-mediated protein crosslinking and stiffening in mouse lenses are inhibited by carboxitin in vitro
Proteins in the eye lens have negligible turnover and therefore progressively accumulate chemical modifications during aging. Carbonyls and oxidative stresses, which are intricately linked to one another, predominantly drive such modifications. Oxidative stress leads to the loss of glutathione (GSH)...
Sparad:
| I publikationen: | Glycoconj J |
|---|---|
| Huvudupphovsmän: | , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2020
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8119300/ https://ncbi.nlm.nih.gov/pubmed/33245448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10719-020-09961-9 |
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