Llwytho...

The Absence of SIRT3 and SIRT5 Promotes the Acetylation of Lens Proteins and Improves the Chaperone Activity of α-Crystallin in Mouse Lenses

Acetylation of lysine residues occurs in lens proteins. Previous studies have shown an improvement in the chaperone activity of αA-crystallin upon acetylation. Sirtuins are NAD(+)-dependent enzymes that can deacylate proteins. The roles of sirtuins in regulating the acetylation of lens proteins and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Exp Eye Res
Prif Awduron: Nandi, Sandip K., Nahomi, Rooban B., Harris, Peter S., Michel, Cole R., Fritz, Kristofer S., Nagaraj, Ram H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504558/
https://ncbi.nlm.nih.gov/pubmed/30849386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2019.02.024
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